As research continues to support the importance of a healthy microbiome, people are rethinking sterilized diets and instead opting for foods and supplements, rich in beneficial bacteria. The best probiotic brands for leaky gut is a regularly searched topic — especially since the microbiome’s inner workings are still largely a mystery. In short, it’s not always easy to know how to find the best supplements. In order to clear up some common questions, Donese Worden, NMD, who specializes in alternative and traditional medicine, weighed in on the matter. “Probiotics can help leaky gut by assisting in the maintenance of normal mucosa (gut wall lining) function and also protecting the lining from injurious factors such as toxins, infections, and allergens,” says Dr. Worden. “One of the important effects of probiotics is to strengthen the epithelial tight junctions. These junctions must be tight so substances don’t leak in or leak out inappropriately.” That said, not all probiotics are created equal — according to Dr. Worden, “As a general rule, a probiotic supplement should provide a minimum of 1 billion CFUs (colony forming units, i.e., viabl...